AKSOPRIL
FOSINOPRIL SODIUM · by AKSON
Composition
Tab10 mg/20 mg: Fosinopril sodium 10 mg/20 mg.
Indications & Dosage
Hypertension: Adult: Initially 10 mg daily for 4 weeks, then increased if necessary up to 40 mg daily, doses over 40 mg not shown to increase efficacy. Congestive heart failure (adjunct): Adult: Initially 10 mg once daily, then increased if tolerated to 40 mg once daily, doses to be increased gradually. Children: Not recommended.
Precautions
Haemodialysis, renal or hepatic impairment, requires close monitoring in patients with hepatic impairment, congestive heart failure, renovascular hypertension, salt and volume depletion
Interactions
Potassium sparing diuretics and potassium supplements, NSAIDs, antacids, lithium, antihypertensives.
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Side Effects
Pruritus, abdominal pain, altered liver function tests, angioedema, arthralgia, blood disorders, bronchospasm, cholestatic jaundice, constipation, diarrhoea, dizziness, dyspepsia, eosinophilia, fatigue, fulminant hepatic necrosis, haemolytic anaemia, headache hepatic failure, hepatitis, hyperkalaemia, hypoglycaemia, leukocytosis, leucopenia, malaise, myalgia, nausea, neutropenia, pancreatitis, paraesthesia, photosensitivity, positive antinuclear antibody, profound hypotension, renal impairment, rhinitis, serositis, sinusitis, thrombocytopenia, urticaria, vasculitis, chest pain, musculoskeletal pain