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Composition

Tab 50 mg/100 mg/200 mg/400 mg: Amisulpride50 mg/100 mg/200 mg/400 mg.

Indications & Dosage

Acute psychotic episode in schizophrenia: Adult: 400-800 mg daily in 2 divided doses, adjusted according to response; max. 1.2 g per day. Schizophrenia with predominantly negative symptoms: Adult: 50-300 mg daily.

Contraindications

Pheochromocytoma, prolactin dependent tumours, comatose states, CNS depression.

Precautions

Cardiovascular disease, conditions predisposing to seizures, depression, Parkinsons disease, blood dyscrasias, diabetes, epilepsy, history of jaundice, myasthenia gravis, prostatic hypertrophy, severe respiratory disease, susceptibility to angle-closure glaucoma, elderly, renal impairment; reduce dose

Pregnancy

Contraindicated

Lactation

Contraindicated

Side Effects

Anxiety, agitation, blood dyscrasias, blurred vision, cardiovascular disorder, confusion, convulsions, difficulty with micturition, dizziness, drowsiness, dry mouth, dystonia, excitement, extra pyramidal symptoms, GI disturbances, headache, hyperglycaemia, leucopenia, hyperprolactineamia, hypotension, insomnia, jaundice (including cholestatic), nasal congestion, photosensitization, rashes, tardive dyskinesia, venous thromboembolism, weight gain. Rare: Neuroleptic malignant syndrome discontinue