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AVAMYS

FLUTICASONE FUROATE · by GSK

NASAL PREPARATIONS Corticosteroid/Nasal decongestant GSK

Composition

Nasal Spray: Fluticasone furoate 27.5 mcg/metered spray; 120 Doses.

Indications & Dosage

Prophylaxis and treatment of allergic rhinitis: Adults: 55 mcg (2 sprays) into each nostril once daily; reduce to minimum effective dose once control achieved; 27.5 mcg (1 spray) into each nostril once daily may be sufficient. Children 6-12 yr: 27.5 mcg (1 spray) into each nostril once daily, increased if necessary to 55 mcg (2 sprays) into each nostril daily; reduce once control achieved; 27.5 mcg (1 spray) into each nostril once daily.

Precautions

Avoid in pulmonary tuberculosis, avoid after nasal surgery (until healed), avoid in the presence of untreated nasal infections (treat infection first), patients transferred from systemic corticosteroids may experience exacerbation of some symptoms, caution in conditions of stress, trauma, surgery, infection, pregnancy and lactation. Monitor patients for signs of adrenal insufficiency, monitor growth in adolescents in prolong therapy

Interactions

Potent inhibitors of CYP3A4

Side Effects

Aggression and anxiety (in children), headache, dryness, epistaxis, hypersensitivity reactions, nasal and throat irritation, nasal ulceration, sleep disturbances, smell disturbances, taste disturbances. Rare: Bronchospasm, anaphylaxis