AZILAAN-C
AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE · by HORIZON
Composition
Tab: Azilsartan Medoxomil and Chlorthalidone 40 mg/12.5 mg, Azilsartan Medoxomil and Chlorthalidone 40 mg/25 mg,
Indications & Dosage
Hypertension, not adequately controlled with monotherapy or high risk of cardiovascular events: Adult: Initially 40/12.5 mg taken orally once daily, dosage may be increased to 40/25 mg after 2 to 4 weeks if needed.
Contraindications
Patients with anuria, coadministeration wth aliskiren-containing products in patients with Diabetes.
Precautions
Heart failure, Severe renal impairment, hepatic impairment. Correct any volume depletion prior to administration the drug, particularly in patients with impaired renal function or those treated with high doses of diuretics. Patients who experience dose-limiting adverse reactions on chlorthalidone may initially be administrated with a lower dose of chlorthalidone.
Interactions
Lithium, non-steroidal anti-inflammatory agents including selective cyclooxygenase-2 inhibitors (cox-2 inhibitors), dual blockade of the renin-angiotensin system (RAS).
Pregnancy
Not recommended
Lactation
Not recommended
Side Effects
Headache, Abdominal pain, Fetal Toxicity, Hypokalemia, Hyperuricemia, Hypotension in Volume- or Salt-Depleted Patients, Diarrhea, Nausea, Elevations of Uric Acid and Cholesterol.