CETROTIDE
CETRORELIX · by MARTIN DOW MARKER
Composition
lnj 0.25 mg: Cetrorelix acetate 250 mcg. Inj 3 mg: Cetrorelix acetate 3000 mcg.
Indications & Dosage
Adjunct in the treatment of female infertility: By SC INJ: Adults (female): Single-dose regimen: 3 mg given when serum oestradiol levels show appropriate stimulation response, usually stimulation day 7 (range days 5-9). If hCG is not administered within 4 days, continue cetrorelix at 0.25 mg/day until hCG is administered. Multiple-dose regimen:250 mcg once daily, dose to be administered in the morning, starting on day 5 or 6 of ovarian stimulation with gonadotrophins (or each evening starting on day 5 of ovarian stimulation), continue throughout administration of gonadotrophin including day of ovulation induction (or evening before ovulation induction), dose to be injected into the lower abdominal wall.
Administration
Administer by SC inj. The needle should be inserted completely into the skin at a 45-degree angle.
Stability
Store in outer carton. Once mixed, solution should be used immediately. 0.25 mg vial: Store under refrigeration at 2C-8C (36F-46F). 3 mg vial: Store at Controlled room temperature at 25C (77F); excursions permitted to 15C-30C (59F-86F).
Contraindications
Moderate to severe renal or hepatic impairment
Precautions
Should only be prescribed by fertility specialist.
Side Effects
Nausea, headache, injection site reactions, rarely hypersensitivity reactions.