CO-CARDIOTEC
ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE · by WILSONS
Composition
Tab10/25 mg: Enalapril maleate 10 mg, hydro-chlorothiazide 25 mg. Tab 5/12.5 mg: Enalapril maleate 5 mg, hydrochlorothiazide 12.5 mg. Tab20/12.5 mg: Enalapril maleate 20 mg, hydrochlorothiazi
Indications & Dosage
Mild to moderate hypertension in patients stabilised on the individual components in the same proportions: Adults: 1 or 2 tab once daily using the strength as clinically appropriate. Children: Not recommended.
Contraindications
Hypersensitivity to any of the ingredient. History of angioneurotic oedema while treating with ACE inhibitors.
Precautions
Impaired renal function, hepatic function, patients undergoing surgery, diabetic patients.
Interactions
Other antihypertensives, lithium, K+ supplements or K+ sparing diuretics, tubocurarine, alcohol, barbiturates, narcotics, antidiabetic agents, corticosteroids, pressor amines, NSAIDs.
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended
Side Effects
Asthenia, blurred vision, depression, dyspnoea, alopecia, anorexia, arrhythmias, confusion, drowsiness, dry mouth, flushing, hyponatraemia, ileus, impotence, insomnia,muscle cramps, nervousness, palpitation, peptic ulcer, sweating, tinnitus, vertigo. Rare: Abnormal dreams, allergic alveolitis, exfoliative dermatitis, glossitis, gynaecomastia, pemphigus, pulmonary infiltrates, Raynauds syndrome, Stevens- Johnson syndrome, stomatitis, toxic epidermal necrolysis