Composition
Tab 80 mg: Nadolol 80 mg
Indications & Dosage
Hypertension: Adult: Initially 80 mg once daily, then increased in steps of up to 80 mg every week if required, max. 240 mg per day. Angina: Adult: Initially 40 mg once daily, then increased if necessary up to 160 mg daily, doses should be increased at weekly intervals, max. dose, max. 240 mg per day. Arrhythmias: Adult: Initially 40 mg once daily, then increased if necessary up to 160 mg once daily, doses should be increased at weekly intervals; reduced to 40 mg daily if bradycardia occurs. Migraine prophylaxis: Adult: Initially 40 mg once daily, then increased in steps of 40 mg every week, adjusted according to response; maintenance 80-160 mg once daily. Thyrotoxicosis (adjunct): Adult: 80-160 mg once daily.
Contraindications
Asthma, cardiogenic shock, Hypotension, marked bradycardia, metabolic acidosis, Phaeochromocytoma, Prinzmetal-s angina, second or third-degree AV block, severe peripheral arterial disease, sick sinus syndrome, heart failure
Precautions
History of obstructive airways disease, renal or hepatic impairment, diabetes, first-degree AV block, myasthenia gravis, portal hypertension, psoriasis, symptoms of hypoglycaemia and thyrotoxicosis may be masked
Pregnancy
Caution advised
Lactation
Aviod
Side Effects
Headache, depression, fatigue, dizziness, dry eye, dyspnoea, erectile dysfunction, heart failure, nausea, paraesthesia, peripheral coldness, peripheral vascular disease, rash, sleep disorders, syncope, visual impairment, diarrhoea, vomiting Atrioventricular block, bronchospasm. Rare: Hallucination, hypoglycaemia