DIARLOPE
LOPERAMIDE · by SHAHEEN
Composition
Cap/Tab 2 mg: Loperamide 2 mg.
Indications & Dosage
Symptomatic treatment of acute diarrhoea: Adults & Children above 12 yrs: Initially 4 mg, followed by 2 mg for up to 5 days, after each loose stool, usual dose 6-8 mg daily; max. 16 mg per day Children 4-7 years: 1 mg 3-4 times a day for up to 3 days only; 8-11 years: 2 mg 4 times a day for up to 5 days; Chronic diarrhoea: Adult: Initially 4-8 mg daily in divided doses, adjusted according to response; maintenance up to 16 mg daily in 2 divided doses. Faecal incontinence: Adult: Initially 500 mcg daily, adjusted according to response, max. daily dose to be given in divided doses, 16 mg per day Pain of bowel colic in palliative care: Adult: 2-4 mg 4 times a day
Contraindications
Conditions where inhibition of peristalsis should be avoided, acute ulcerative colitis, pseudo membranous colitis, abdominal disten-sion.
Precautions
Acute dysentery, hepatic impairment, children below 12 years.
Pregnancy
Advised to avoid
Lactation
Advised to avoid
Side Effects
Dizziness, flatulence, headache, nausea, abdominal pain, drowsiness, dry mouth, dyspepsia, rash, vomiting. Rare: fatigue, hypertonia, paralytic ileus, Stevens-Johnson syndrome, toxic epidermal necrolysis, urinary retention.