DIPROS
DICLOFENAC SODIUM AND MISOPROSTOL · by HELIX
Composition
Tab 50/0.2 mg: Diclofenac sodium 50 mg, mis-oprostol 0.2 mg. Tab 75/0.2 mg: Diclofenac sodium 75 mg, misoprostol 0.2 mg.
Indications & Dosage
Prophylaxis against NSAIDs induced gastric ulceration in rheumatoid arthritis, osteoarthrosis: Adults: 1 tab of 50 mg two-three times daily or 1 tab of 75 mg two times daily. Children: Not recommended.
Contraindications
Active peptic ulcer, aspirin/anti-inflammatory induced allergy, women planning pregnancy
Precautions
History of GIlesions, renal, hepatic or cardiac impair-ment, cerebrovascular coronary or peripheral disease, premenopausal women should use effective contraception. Monitor patients on long-term treatment.
Interactions
Salicylates, methotrexate, lithium, digoxin, diuretics, cyclosporin, anticoagulants, oral hypoglycaemics, quinolones, NSAIDs, steroids.
Pregnancy
Contraindicated in pregnancy
Lactation
Contraindicated or not recommended.
Side Effects
Menorrhagia, intermenstrual bleeding, skin reactions, headache, dizziness, oedema, depression, diarrhoea, drowsiness, fluid retention, GI disturbances, haematuria, headache, hearing disturbances, hypersensitivity reactions, insomnia, nausea, nervousness, photosensitivity, raised blood pressure, rashes