ENTROTIL
DIPHENOXYLATE AND ATROPINE · by DANAS
Composition
Tab: Diphenoxylate HCI 2.5 mg, atropine Sulphate 25 mcg.
Indications & Dosage
Diarrhoea: Adults: Initially 4 tab, then 2 tab six hourly until controlled. Children below 5 yr: not recommended; 5-8 yr:1 tab three times daily; 9-12 yr:1 tab four times daily; 13-16 yr:2 tab three times daily.
Contraindications
Intestinal obstruction, acute ulcerative colitis, Pseudomembranous colitis, Crohns disease, hepatic dysfunction.
Precautions
Dehydration or electrolyte imbalance should be treated before initiating therapy, young children, inflammatory bowel disease, hepatic impairment.
Interactions
MAOIs, CNS depressants.
Pregnancy
Not recommended.
Lactation
Caution advised.
Side Effects
Pancreatitis, paralytic ileus, hyperglycemia, hemorrhagic colitis, toxic megacolon, CNS disturbances, allergic reactions, pseudomembranous colitis, anaphylactoid reaction.