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EPHEDRINE

EPHEDRINE HCl · by JAWA

DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, SYSTEMIC : Indirectly-acting sympathomimetic/ Vasoconstrictor JAWA

Composition

Inj/Tab: Ephedrine HCI 30 mg.

Indications & Dosage

Reversal of hypotension from spinal or epidural Anaesthesia: BY SLOW IV INJ: Adult: 3-6 mg every 3-4 minutes (max. per dose 9 mg), adjusted according to response; max.30 mg per course. Children 1-12 yr: 500-750 mcg/kg or 17-25 mg/square meter every 3-4 min according to response, max 30 mg during episode; 12-18 yr: 3-7.5 mg, max 9 mg repeated every 3-4 minutes according to response, max 30 mg per course. Reversible airways obstruction: ORAL: Adult: 15-60 mg 3 times a day Children above 4 yr: 10 mg three times daily. Neuropathic oedema: ORAL: Adult: 30-60 mg 3 times a day.

Administration

Administer by SC, IM or slow IV route,IV injection of a solution containing ephedrine hydro-chloride 3 mg/ml

Compatibility

ompatible with D5W, 010W, Ringer solution, LR, NS, 0.45% NS.

Contraindications

Coronary disease, hyperthyroidism, hypertension, prostatic hypertrophy, closed angle glaucoma, hyperexcitibility

Precautions

Diabetes, severe renal and hepatic impairment, cardiac disorder

Interactions

MAOls, anaesthetics, TCADs.

Pregnancy

Caution advised

Lactation

Caution advised

Side Effects

GI distress, headache, nausea, anxiety, restlessness, insomnia, tremor, arrhythmia.