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ERGOVIN

METHYLERGOMETRINE MALEATE · by BROOKES

UTEROTONICS Uterotonic: Ergot alkaloid BROOKES

Composition

Tab 0.125 mg: Methylergometrine maleate 0.125 mg. Inj: Per 1 ml amp: Methylergometrine maleate 0.2 mg.

Indications & Dosage

Management of puerperium, postpartum haemorrhage, uterine haemorrhage, uterine subinvolution, uterine atonia (Adjunct): By IV INJ: Adults: 0.5 ml IV or 1 ml IM after delivery of placenta. ORAL: Adults: 1 tab 3-times daily for three to four days in puerperium. Children: Not applicable.

Administration

IV: Ampoules containing discoloured solution should not be used: Administer over no less than 60 seconds.

Contraindications

Induction of labour, threatened spontaneous abortion, toxaemia, heart disease, labour augmentation, peripheral obliterative vascular disease, arteriovenous shunt, hypertention

Precautions

Caution in patients with sepsis, obliterative vascular disease.

Interactions

Antifungals, CYP3A4 inhibitors, sumatriptan, sibutramine and other serotonin agonists.

Side Effects

Vascular complications, ischemia, gangrene, coma, hypertension, angina, confusion, chest pain, palpi-tation, dizziness, hallucinations, seizures, headache, nausea, vomiting, diarrhoea, leg cramps, hematuria, dyspnoea, nasal congestion, tinnitus.