FAGASTRIL
FAMOTIDINE · by GRAYS
Composition
Cap 20 mg/40 mg: Famotidine 20 mg/40 mg. Susp: Per 5 ml: Famotidine 10 mg. Tab 10 mg/20 mg/40 mg: Famotidine 10 mg/20 mg/40 mg. Tab Chewable/Dispersible 10 mg/20 mg/40 mg: Famotidine 10 mg/2
Indications & Dosage
Treatment of benign gastric and duodenal ulceration: Adult: 40 mg once daily for 4-8 weeks, dose to be taken at night. Prophylaxis of duodenal ulcer relapse: Adult: 20 mg once daily, dose to be taken at night. Zollinger-ellison syndrome: Initially 20 mg every 6 hr, adjust as necessary; max 800 mg daily. Reflux oesophagitis: Adult: 20-40 mg twice daily for 6-12 weeks; maintenance 20 mg twice daily
Contraindications
Hypersensitivity, gastric malignancy.
Precautions
Gastric carcinoma Impaired, renal impairment, liver impairment.
Pregnancy
Avoid unless potential benefit outweighs risk.
Lactation
Not recommended.
Side Effects
Blood dyscrasias, hypotension, tachycardia, emesis, headache, dizziness, constipation, diarrhoea, nausea, dry mouth, bradycardia, anorexia, cholestatic jaundice, anaphylaxis, angioedema, arthralgia, muscle cramp,renal failure, abnormal liver enzymes, CNS disturbances. Rarely reversible gynaecomastia, toxic epidermalnecrolysis, chest tightness, interstitial pneumonia, paraesthesia, seizures