HIERRO
DEFERIPRONE · by SCHAZOO PHARMA
Composition
Tab/Cap 250 mg/500 mg: Deferiprone 250 mg/500 mg
Indications & Dosage
Treatment of iron overload in patients with thalassaemia major in whom desferrioxamine is contraindicated or is inadequate: Adult & Children: 25 mg/kg 3 times a day; max. 100 mg/kg per day.
Contraindications
History of agranulocytosis orrecurrent neutropenia, pregnancy & lactation.
Precautions
Monitor neutrophil count, serum ferritin & Zinc concentration regularly. Discontinue if infection develops. Caution in renal & hepatic impairment and children.
Interactions
Aluminium containing antacids.
Side Effects
Agranulocytosis, headache, arthropathy, blood dyscrasias, GI disturbances, increased appetite, neutropenia, red-brown urine discoloration, zinc deficiency