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Composition

Tab 1 mg/2 mg/5 mg: Terazosin (as HCI) 1 mg/2 mg/5 mg.

Indications & Dosage

Mild to moderate hypertension: Adult: 1 mg daily for 7 days, then increased if necessary to 2 mg daily, to be taken at bedtime; maintenance 2-10 mg once daily, doses above 20 mg rarely improve efficacy. Benign prostatic hyperplasia: Adult: Initially 1 mg daily, dose should be taken at bedtime, if necessary dose may be doubled at intervals of 1-2 weeks according to response; maintenance 5-10 mg daily; max. 10 mg per day Children: Not recommended.

Precautions

History of syncope. Avoid rapid increase in dose.

Interactions

Beta-blockers, diuretics, ACE inhibitors, calcium channel blockers, sildenafil, tadalafil, vardenafil, NSAIDs, pressor agents (norepinephrine).

Pregnancy

Use only when potential benefit outweighs risk.

Lactation

Caution advised

Side Effects

Angioedema, asthenia, back pain, blurred vision, decreased libido, depression, dizziness, drowsiness, dry mouth, dyspnea, erectile disorders, GI disturbances, headache, hypersensitivity reactions, hypotension, intra-operative floppy iris syndrome, nervousness, oedema, pain in extremities, palpitations, paraesthesia, postural hypotension, priapism, pruritus, rash, rhinitis, syncope, tachycardia thrombocytopenia, weight gain