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ISONEFRINE

PHENYLEPHRINE, EYE · by LCPW

Composition

Eye Drop 0.12%/2.5%/10%: Phenylephrine HCI 0.12%/2.5%/10%.

Indications & Dosage

Mydriasis: Adult & Children: Apply 1 drop 30-60 min before procedure, then apply 1 drop after 60 minutes if required, a drop of topical anaesthetic may be applied to the eye a few minutes before using phenylephrine to prevent stinging. Vasoconstriction, Pupil dilation: Adults: 1 drop as required. Uveitis: Adults: 1 drop as required, may be continued the following day. Ophthalmic irritation: Adults: 1-2 drops of 0.12% into affected eye (s), upto four times per day.

Contraindications

10% strength eye drops in children and the elderly, aneurysms, cardiovascular disease, hypertension, thyrotoxicosis, hyperthyroidism, diabetes.

Precautions

Asthma, cerebral arteriosclerosis, corneal epithelial damage, darkly pigmented iris, diabetes, mydriasis can precipitate acuteangle-closure glaucoma in a few patients, ocular hyperaemia, susceptibility to angle-closure glaucoma

Interactions

sympathomimetics, vasoconstrictor

Pregnancy

Use only if potential benefit outweighs risk

Lactation

Use only if potential benefit outweighs risk

Side Effects

Arrhythmias, blurred vision, conjunctivitis, coronary artery spasm, extrasystoles, hyperaemia, hypertension, local irritation, myocardial infarction (after use of 10% strength in patients with pre-existing cardiovascular disease), oedema, palpitation, photophobia, raised intraocular pressure, tachycardia, transient stinging