LIPARD
PALIPERIDONE · by SHROOQ
Composition
Tab 1.5 mg/3 mg: Paliperidone 1.5 mg/3 mg
Indications & Dosage
Schizophrenia, Psychotic or manic symptoms of schizoaffective disorder: Adult: Initially 1.5-3 mg once daily with breakfast or on an empty stomach, increased to 6 mg once daily, then increased in steps of 3 mg if required, dose to be adjusted over at least 5 days; usual dose 3-12 mg daily.
Precautions
Caution in severe hepatic impairment, cataract surgery; risk of intraoperative floppy iris syndrome, dementia with Lewy bodies, elderly, patients with risk factors for stroke, predisposition to GI obstruction, prolactin-dependent tumours, renal impairment; reduced dose
Interactions
Sedatives, CNS depressants, use of disulfiram concomitent is not recommended.
Pregnancy
Use only if potential benefit outweighs risk
Lactation
Causion advised avoid
Side Effects
Arthralgia, anxiety, depression, hypertension, epistaxis, malaise, myalgia, oedema, respiratory disorders, sleep disorders, urinary disorders, elevated plasma-cholesterol concentrations, elevated plasma-triglyceride concentrations, hypoaesthesia, paraesthesia, tinnitus, visual disorders. Rare: Antidiuretic hormone secretion, intestinal obstruction, intra-operative floppy iris syndrome, pancreatitis, pulmonary embolism, rhabdomyolysis