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Composition

Tab: Nimesulide 100 mg.

Indications & Dosage

Painful inflammatory conditions including osteoarthritis, postoperative trauma, sports injuries, ear, nose and throat disorders, dental surgery, bur-sitis/tendinitis, thrombophlebitis, pharyngitis: Adults: 100 mg twice daily. Children: Not recommended.

Contraindications

Active GI bleeding or ulceration, history of GI bleeding or perforation related to previous NSAID therapy, history of recurrent GI haemorrhage or ulceration, severe heart failure, moderate to severe hepatic impairment.

Precautions

Patients with renal impairment (particularly elderly patients), ischaemic heart disease, peripheral arterial disease, risk factors for cardiovascular events, ulcerative colitis (may be exacerbated), uncontrolled hypertension, renal or hepatic impairment, monitor on long--term therapy, asthma, congestive heart failure or cirrhosis or those patients who are volume or salt depleted.

Pregnancy

Contraindicated in pregnancy.

Lactation

Contraindicated

Side Effects

Abdominal pain, angioedema, blood disorders, bronchospasm, colitis, Crohns disease, depression, diarrhoea, dizziness, drowsiness, fluid retention, GI bleeding and ulceration, GI disturbances, haematuria, headache, hearing disturbances, hypersensitivity reactions, nausea, nervousness, photosensitivity, raised blood pressure, rashes, renal failure (especially in patients with preexisting renal impairment)