Composition
Cap 67 mg/100 mg/134 mg/200 mg/300 mg: Fenofibrate 67 mg/100/134 mg/200 mg/300 mg. Tab 67 mg/160 mg: Fenofibrate 67 mg/160 mg.
Indications & Dosage
Types Ila, Ilb, Ill, IV, V hyperlipidaemia, including familial hypercholesterolaemia: Adults: Initially 200 mg once daily with food or 67 mg 3 times daily. Children 4-15 yrs: one 67 mg cap/20 kg body-weight, max 4 cap of 67 mg or max 3 cap of 67 mg with concomitant statin daily; 15-18 yr: initially 3 cap of 67 mg daily, increased if necessary to 4 cap of 67 mg daily, max 3 cap of 67 mg daily with concomitant statin. Severe hyperlipidaemia: Adult: 267 mg once daily with food.
Contraindications
Severe renal or hepatic dysfunction, gall bladder disease, photoallergy or phototoxic reactions with fibrates or ketoprofen.
Precautions
Monitor liver enzymes, renal or hepatic impairment, pancreatitis. Correct hyperthyroidism before initiating treatment
Interactions
Anticoagulants, cyclosporin, statins, fibrates.
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Side Effects
Hepatitis, rhahdomyolysis, GI upset, skin rashes, headache, fatigue, vertigo, myalgia, gallstones. Rare: Sexual asthenia, muscle toxicity (discontinue), hepatitis, alopecia, photosensitivity, interstitial pneumopathies.