Composition
Tab: Carbimazole 5 mg.
Indications & Dosage
Hyperthyroidism: Adult: 15-40 mg daily continue until the patient becomes euthyroid, usually after 4 to 8 weeks, higher doses should be prescribed under specialist supervision only, then reduced to 5-15 mg daily, reduce dose gradually, therapy usually given for 12 to 18 months Children: Initially, 5-15 mg daily in divided doses. Thyrotoxicosis: Adults: Initially, 20-60 mg daily in two or three divid-ed doses until patient is euthyroid. Maintenance; 5-15 mg daily for 6-18 months, Alternatively, continue with 20-60 mg daily and supplemental thyroxine 50-150 mcg daily for 6-18 months. Children: Initially, 5-15 mg daily in divided doses.
Contraindications
Tracheal obstruction, severe blood disorders.
Precautions
Warn patients to inform doctor if sore throat, mouth ulcers, bruising, fever, malaise or non-specific illness develops.
Pregnancy
Caution advised
Lactation
Contraindicated
Side Effects
Arthralgia, fever, headache, jaundice, malaise, mild GI disturbances, nausea, pruritus, rash, taste disturbance. Rare: Agranulocytosis, alopecia, bone marrow Suppression, jaundice, myopathy, pancytopenia