NERISONE
DIFLUCORTOLONE VALERATE, TOPICAL · by OBS
Composition
Cream/Fatty Oint/Oint: Diflucortolone valerate 0.1%. Forte fatty Oint: Diflucortolone valerate 0.3%.
Indications & Dosage
Severe inflammatory skin disorders such as eczemas, Short-term treatment of severe exacerbations, Psoriasis: Adult & Children: Apply 1-2 times a day for up to 2-4 weeks, reducing strength as condition responds, to be applied thinly; max. 60 g per week.
Contraindications
Acne, perioral dermatitis, widespread plaque psoriasis, rosacea, bacterial, fungal or viral skin lesions such as impetigo, paronychia, erysipelas, cellulitis, angular cheilitis, erythrasma, treatment of rosacea, peri-oral dermatitis or acne, use on face, groin or axilla
Precautions
Avoid prolonged use, keep away from eyes, under specialist supervision in psoriasis (can result in rebound relapse, development of generalized pustular psoriasis, and local and systemic toxicity). Do not use steroid as sole therapy in psoriasis. Do not use steroids to treat diaper dermatoses in infants. If local irritation develops discontinue use.
Side Effects
Burning, itching, irritation, erythema, dryness, folliculitis, hypertrichosis, pruritus, acneiform eruptions, hypo-pigmentation, peri-oral dermatitis, allergic contact dermatitis, maceration of the skin, thinning of the skin (the original structure may never return),worsening of acne and rosacea, skin atrophy, striae, malaria, telangiectasia. Rare: Adrenal suppression, Cushings syndrome