ORGALUTRAN
GANIRELIX · by OBS
Composition
Inj: Ganirelix 0.25 mg
Indications & Dosage
Adjunct in the treatment of female infertility (initiated under specialist supervision): BY SC INJ: Adult: 0.25 mg once daily in the morning (or each afternoon) starting on day 5 or day 6 of ovarian stimulation with gonadotrophins, continue throughout administration of gonadotrophins including day of ovulation induction.
Administration
Subcutaneous injection to be injected preferably into the upper leg (rotate injection sites to prevent lipoatrophy)
Contraindications
Abnormal uterine bleeding of undetermined cause, hormone-dependent tumours, moderate to severe renal or hepatic impairment, endometrial carcinoma, severe allergic reactions.
Precautions
Ectopic pregnancy, incidence of multiple births increased, ovarian hyperstimulation syndrome, polycystic ovary syndrome, uterine fibroids. Exclude pregnancy before treatment. Patients sensitive to pituitary gonadotrophins.
Pregnancy
Contraindicated
Lactation
Contraindicated
Side Effects
Abdominal discomfort, breast tenderness, dizziness, endometriosis, headache, hot flushes, insomnia, inter-menstrual spotting, menorrhagia, nausea, ovarian hyper-stimulation (withdraw), rashes, vomiting, weight gain