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OZAC

OZAGREL · by GRATON

ANTITHROMBOTIC AGENTS Thromboxane synthetase inhibitor GRATON

Composition

: Ozagrel sodium 20 mg/ 40 mg/80 mg; vial.

Indications & Dosage

Treatment of acute thrombotic cerebral infarction or disturbance on motor functions: Adults: 80 mg, twice a day, solute in 500 ml normal saline or 5% glucose solution, IV INF, for a duration of 2 weeks. Children: Not recommended

Contraindications

Cerebral haemorrhage or cerebral infarction with haemorrhage, deep coma accompanied large area cerebral infarction, severe impairment on heart, lung, liver, kidney, such as severe arrhythmia or cardiovascular infarction, Hemopathy or hemorrhagic tendency, Severe hyper-tension, with a contracting pressure of 200 mmHg.

Side Effects

Nausea, vomiting, diarrhoea, anorexia, abdominal distension, urticaria, skin rash, occasional increase of GOT, OPT. BUN. Risk of bleeding; careful observation is needed, stop the administration once such symptom appears, supraventricular arrhythmia and hypotension; decrease the amount or stop the administration, headache, fever, pain at the injection site, shock or thrombocytopenia, haemorrhagic cerebral infarction, extradural, encephalic, gastrointestinal and subcutaneous haemorrhage.