QUADREX
NALTREXONE HCl · by HORIZON
Composition
Tab: Naltrexone 50 mg
Indications & Dosage
Adjunct to prevent relapse in formerly opioid-dependent patients (under specialist supervision): Adult: Initially 25 mg daily, then increased to 50 mg daily, dose may be divided and given on 3 days of the week; max. 350 mg per week. Adjunct to prevent relapse in formerly alcohol-dependent patients (under specialist supervision): Adult: 25 mg once daily on the first day, then increased if tolerated to 50 mg daily.
Contraindications
Patients currently dependent on opioids, severe renal impairment, severe or acute hepatic impairment, acute hepatitis, or hepatic failure
Precautions
Caution in mild to moderate hepatic impairment, caution in mild to moderate renal impairment.
Pregnancy
Use only if potential benefit outweighs risk
Lactation
Caution advised, Avoid
Side Effects
Anxiety, headache, dizziness, arthralgia, asthenia, chest pain, chills, constipation, diarrhoea, hyperhidrosis, mood altered, myalgia, nausea, palpitations, sexual dysfunction, skin reactions, sleep disorders, tachycardia, thirst, abdominal pain, vomiting, alopecia, confusion, depression, drowsiness, dry mouth, flatulence, flushing, hallucination, lymphadenopathy, paranoia, peripheral coldness, seborrhoea, sinus disorder, tinnitus, tremor, ulcer, urinary disorders, vertigo, vision disorders. Rare: Immune thrombocytopenic purpura, rhabdomyolysis, suicidal behaviours.