SOFVASC OLM
AMLODIPINE AND OLMESARTAN MEDOXOMIL · by WILSONS
Composition
Tab20/5mg: Olmesartan medoxomil 20 mg, Amlodipine (as besylate) 5 mg. Tab 20/10 mg: Olmesartan medoxomil 20 mg, Amlodipine (as besylate) 10 mg. Tab 40/5 mg: Olmesartan medoxomil 40 mg, amlo
Indications & Dosage
Hypertension in patients stabilised on the individual components in the same proportions: Adults: 1 tab daily using the strength as clinically appropriate. Children: Not recommended.
Contraindications
Hepatic or severe renal impairment, cardiogenic shock, acute MI, unstable angina.
Precautions
Salt or volume depletion, severe congestive heart failure, renal disease, renal artery stenosis, aortic or mitral valve stenosis, obstructive hypertrophic cardiomyopathy, primary aldosteronism. Mild to moderate renal impairment; monitor serum potassium in patients at risk of hyperkalaemia.
Interactions
Lithium, K-supplements, K+-sparing diuretics, salt substitutes, NSAIDs, CYP3A4 inducers and inhibitors, sildenafil.
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Side Effects
Arthritis, chest pain, cough, fatigue, GI disturbances, haematuria, hypertriglyceridaemia, hyperuricaemia, influenza-like symptoms, musculoskeletal pain, peripheral oedema, pharyngitis, rhinitis, urinary-tract infection. Rare: Angina, vertigo, headache, myalgia, pruritus, thrombocytopenia, urticaria