STEER
BUSPIRONE · by VALOR
Composition
Tab 5 mg/10 mg/30 mg: Buspirone HCI 5 mg/10 mg/30 mg.
Indications & Dosage
Anxiety short-term management: Adult: 5 mg 2-3 times a day, increased if necessary up to 45 mg daily, dose to be increased at intervals of2-3 days; usual dose 15-30 mg daily in divided doses.
Contraindications
Acute porphyrias, epilepsy, severe renal or hepatic impairment.
Precautions
History of renal or hepatic impairment. Reduce dose in mild to moderate hepatic impairment; avoid in severe disease. Reduce dose in renal impairment; avoid if eGFR less than20 -/minute/1.73m. Withdraw benzodiazepines gradually if transferring to buspirone.
Interactions
MAOIs, rifampicin, erythromycin, ritonavir, itra-conazole, diltiazem, verapamil, grape-fruit juice, anticonvulsants.
Pregnancy
Avoid.
Lactation
Contraindicated
Side Effects
Headache, nervousness, dizziness, tachycardia, chest pain, confusion, dry mouth, fatigue.