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STIBOTIM

SODIUM STIBOGLUCONATE · by STAR

Composition

Inj: Per ml: Sodium stibogluconate 100 mg.

Indications & Dosage

Visceral leishmaniasis: BY IV INJ, OR BY IM INJ: Adult: 20 mg/kg daily for 28 days. Cutaneous leishmaniasis: BY IV INJ, OR BY IM INJ: Adult: 20 mg/kg daily for 20 days.

Precautions

Heart disease (withdraw if conduction disturbances occur), mucocutaneous disease, predisposition to QT interval prolongation, treat intercurrent infection (e.g. pneumonia), administer IV injection very slowly to reduce risk of local thrombosis and stopped if coughing or substernal pain, renal and hepatic impairment, monitor ECG during administration

Pregnancy

Use only if potential benefit outweighs risk.

Lactation

Caution advised

Side Effects

Abdominal pain, anorexia, nausea, vomiting, pain on injection site, diarrhoea, ECG changes, cough, headache, lethargy, arthralgia, flushing myalgia, vertigo, fever, sweating, rash, pancreatitis, anaphylaxis. Rare: Bleeding from gums and nose, jaundice, substernal pain, sweating, vertigo