Composition
Syp 12.5 mg: Per 5 ml: Diphenhydramine 12.5 mg
Indications & Dosage
Symptomatic relief of allergic symptoms caused by histamine release, adjunct to epinephrine in the treatment of anaphylaxis, management of Parkinsonian syndrome including drug-induced extra pyramidal symptoms: Adults: 2-4 tsp syrup 3-4 times daily; max 150 mg/day. Children 2-6 yrs: 1/2 tsp every 4 hr; max 37.5 mg/day; 6-12 yrs: 1-2 tsp every 4 hr; max 150 mg/day; above 12 yrs: same as adult.
Contraindications
Acute porphyrias, hypersensitivity, Avoid in severe liver disease; increased risk of coma, pregnancy and lactation.
Precautions
Caution in patients in narrow angle glaucoma, pyloroduodenal obstruction, urinary tract obstruction, urinary tract obstruction, hyperthyroidism, increased intraocular pressure, cardiovascular disease, severe renal impairment, epilepsy, prostatic hypertrophy
Interactions
CNS depressants, nebivolul tamoxifen, tramadol, amphetamines, fesoterodine.
Pregnancy
Contraindicated
Lactation
Contraindicated
Side Effects
Anorexia, fatigue, confusion weakness, restlessness, lethargy, dry mouth, constipation, blurred vision, drowsiness, bloating, drowsiness, tremor, jaundice, hepatic dysfunction, granulocytopenia, hypertension, euphoria, hallucinations, palpitations, decreased libido, ataxia, skin rash, urticaria, early menses, urinary frequency, urinary retention, purpura, eosinophilia, thrombocytopenia, agranulocytosis, nausea, vomiting, diarrhoea, weight gain, wheezing, tightness of chest, thickening of bronchial secretions.