Composition
Tab 125 mg/250 mg: Terbinafine 125 mg/250 mg (as NCI).
Indications & Dosage
Tineapedis: Adult: 250 mg once daily for 2-6 weeks. Tineacorporis: Adult: 250 mg once daily for 4 weeks. Tineacruris: Adult: 250 mg once daily for 2-4 weeks. Dermatophyte infections of the nails: Adult: 250 mg once daily for 6 weeks-3 months (longer duration in toenail infections). Cutaneous candidiasis, Pityriasis versicolor: Adult: 250 mg once daily for 3-4 weeks.
Contraindications
Hypersensitivity to terbinafine.
Precautions
Autoimmune disease (risk of lupus erythematosus-like effect), psoriasis (risk of exacerbation), chronic liver dysfunction or impaired renal function.
Interactions
Cyclosporin, tolbutamide, oral contraceptives, rifampicin, cimetidine.
Pregnancy
Caution advised, avoid
Lactation
Contraindicated, avoid
Side Effects
Taste disturbance, GI disturbance, abdominal discomfort, anorexia, arthralgia, diarrhoea, dyspepsia, headache, myalgia, nausea, rash, urticaria. Rare: Cholestasis, dizziness, hepatitis, hypoaesthesia, jaundice, liver toxicity, malaise, paraesthesia, blood disorders, lupus erythematosus-like effect, exacerbation of psoriasis