Composition
Cap 2 mg/4 mg: Tolterodine 2 mg/4 mg. Tab 1 mg/2 mg: Tolterodine 1 mg/2 mg.
Indications & Dosage
Urinary frequency, Urinary urgency, Urinary incontinence: Adult: 2 mg twice daily, reduced if not tolerated to 1 mg twice daily.
Contraindications
Urinary retention, uncontrolled narrow angle glaucoma, myasthenia gravis, severe ulcerative colitis, toxic megacolon.
Precautions
Bladder outlet or GI obstruction, renal or hepatic impairment, autonomic neuropathy, hiatus hernia, history of QT-interval prolongation
Interactions
Potent CYP3A4 inhibitors such as azole antifungals or macrolides. Anticholinergics, muscarinic agonists, metoclopride, cisapride.
Pregnancy
Risk cannot be ruled out.
Lactation
Contraindicated or not recommended.
Side Effects
Bronchitis, chest pain, fatigue, paraesthesia, peripheral oedema, sinusitis, vertigo, weight gain, memory impairment, flushing, dry mouth, GI upset, headache,