TIGESIC
TIZANIDINE · by NABIQASIM
Composition
Tab 2 mg/4 mg/6 mg: Tizanidine (as HCI) 2 mg/4 mg/6 mg.
Indications & Dosage
Spasticity associated with multiple sclerosis or spinal cord injury or disease: Adult: Initially 2 mg daily, then increased in steps of 2 mg daily in divided doses, increased at intervals of at least 3-4 days and adjust according to response; usual dose up to 24 mg daily in 3-4 divided doses; max. 36 mg per day.
Precautions
Impaired liver or kidney function, elderly
Interactions
Antihypertensives, diuretics, alcohol, sedatives. Caution with concomitant administration of drugs that prolong QT interval.
Pregnancy
Avoid
Lactation
Avoid
Side Effects
Altered liver enzymes (discontinue if persistently raised), dizziness, drowsiness, dry mouth, fatigue, GI disturbance, hypotension, nausea, bradycardia, asthenia, blurred vision, confusion, convulsions, hallucinations, hepatitis, insomnia, liver Failure, syncope