TOBITIL
TENOXICAM · by WILSHIRE
Composition
Tab/Cap: Tenoxicam 20 mg.
Indications & Dosage
Pain and inflammation in rheumatic disease: Adult: 20 mg once daily. Pain and inflammation in acute musculoskeletal disorders including osteoarthrosis: Adult: 20 mg once daily for 7 days; max. duration of treatment 14 days Children: Not recommended.
Contraindications
Active GI bleeding or ulceration, history of GI bleeding or perforation related to previous NSAID therapy, history of recurrent GI haemorrhage or ulceration (two or more distinct episodes), severe heart failure, aspirin/anti-inflammatory induced allergy, hepatic and renal failure
Precautions
Allergic disorders, cardiac impairment, cerebrovascular disease, coagulation defects, connective-tissue disorders, Crohns disease, elderly, heart failure, ischaemic heart disease,peripheral arterial disease, risk factors for cardiovascular events, ulcerative colitis (may be exacerbated), uncontrolled hypertension, renal or hepatic impairment, monitor on long-term therapy, asthma
Interactions
Alcohol, CNS depressants
Pregnancy
Use only when no safer alternative exists for a seri-ous problem.
Lactation
Caution advised, avoid
Side Effects
Abdominal pain, angioedema, blood disorders, bronchospasm, colitis, Crohns disease, depression, diarrhoea, dizziness, drowsiness, fluid retention, GI bleeding and ulceration, GI disturbances,haematuria,headache, hearing disturbances, hypersensitivity reactions, nausea, nervousness, photosensitivity, raised blood pressure, rashes, renal failure (especially in patients with preexisting renal impairment),tinnitus, vertigo. Rare: Hepatic damage, interstitial fibrosis associated with NSAIDs,Stevens-Johnson syndrome, toxic epidermal necrolysis, visual disturbances, exacerbation of symptoms in asthma, thrombocytopenia, aseptic meningitis, CNS disturbances.