TRIFORGE
AMLODIPINE, VALSARTAN AND HYDROCHLOROTHIAZIDE · by HIGHNOON
Composition
Tab10/160/12.5 mg: Amlodipine 10 mg, valsartan 160 mg, hydrochlorothiazide 12.5 mg. Tab10/160/25 mg: Amlodipine 10 mg, valsartan 160 mg, hydrochlorothiazide 25 mg. Tab10/320/25 mg: Amlodipine
Indications & Dosage
Hypertension not adequately controlled by valsartan and amlodipine: Adults: 1 tab daily using the strength as clinically appropriate. Children: Not recommended.
Contraindications
Biliary cirrhosis or cholestasis.
Precautions
Patients with activated renin-angiotensin system that are receiving angiotensin receptor blockers, hepatic impairment or biliary obstructive disorders, aortic or mitral stenosis or obstructive hypertrophic cardiomyopathy, hyperkalaemia.
Interactions
K supplements, K-sparing diuretics, K-containing salt substitutes or other drugs that may increase K levels (heparin, etc.)
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Side Effects
Renal impairment, cough, fatigue, GI disturbance, headache, syncope, hypersensitivity reactions, myalgia, neutropenia, pruritus, rash,serum sickness, thrombocytopenia, vasculitis, nasopharyngitis, flu, oedema (pitting, facial, peripheral), flushing, asthenia, hot flush.