Composition
Tab: Furosemide 40 mg, amiloride HCI 5 mg.
Indications & Dosage
Oedema, Prompt diuresis where potassium conservation is important: Adults: 1-2 tab in the morning. Elderly, adjust ac-cording to renal function, response and electrolyte levels. Children: Not recommended.
Contraindications
Severe or progressive renal failure, Addisons disease, anuria, comatose or precomatose states associated with liver cirrhosis, dehydration, hyperkalaemia, hypovolaemia, severe hypokalaemia, severe hyponatraemia, electrolyte imbalance.
Precautions
Correct hypovolaemia before using in oliguria, diabetes mellitus, elderly, gout, hepato-renal syndrome, hypoproteinaemia, hypotension, impaired micturition, prostatic enlargement. Monitor fluid and electrolyte levels regularly.
Interactions
K+ supplement, K+-sparing diuretics (avoid), Lithium, nephrotoxic or ototoxic antibiotics, NSAIDs, digitalis, antihypertensives, antidiabetics, non-depolarising muscle relaxants
Pregnancy
Risk cannot be ruled out.
Lactation
Contraindicated or not recommended.
Side Effects
Agranulocytosis, anaphylaxis, aplastic anaemia, blood disorders, bone marrow depression (discontinue), confusion, deafness, eosinophilia, GI disturbances, gout, haemolytic anaemia, hepatic encephalopathy, hyperglycaemia, hyperuricaemia, hypocalcaemia, hypokalaemia, hypomagnesaemia, hyponatraemia, hypotension, intrahepatic cholestasis, leucopenia, metabolic alkalosis or acidosis, pancreatitis, paraesthesia, photosensitivity, purpura, Stevens-Johnson syndrome, temporary increase in serum cholesterol and triglyceride concentrations, thrombocytopenia, tinnitus, toxic epidermal necrolysis