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VASTOR-AM

ATORVASTATIN AND AMLODIPINE · by ATCO

LIPID MODIFYING AGENTS Calcium antagonist/Statin ATCO

Composition

Tab5/10 mg: Amlodipine besylate 5 mg, atorvastatin 10 mg.Tab5/20 mg: Amlodipine besylate 5 mg, atorvastatin 20 mg.Tab10/10 mg: Amlodipine besylate 10 mg, atorvastatin 10 mg.Tab10/20 mg: Amlo

Indications & Dosage

Prevention of Cardiovascular complications, Cardiovascular risk due to hypertension & dyslipidaemia and/or chronic stable angina: Adults: 1 tab of Amlodipine/Atorvastatin range from 5 mg/10 mg to a max dose of 10 mg/80 mg once daily. Children: Not recommended.

Contraindications

Active liver disease or unexplained persistent elevations of serum transaminases >3x the upper limit of normal. Women of childbearing potential who are not using adequate contraceptive measures

Precautions

Heart failure, impaired hepatic function; perform liver function tests before initiating treatment & periodically thereafter, history of liver disease, discontinue drug if markedly elevated CPK levels occur or myopathy is diagnosed or suspected, risk factor predisposing to development or renal failure

Interactions

Cyclosporin, fibric acid derivative, erythromycin, clarithromycin, azole antifungals, niacin, oral antacid suspension containing magnesium hydroxide, aluminium hydroxide, colestipol, digoxin, norethindrone and ethinylestradiol.

Pregnancy

Contraindicated in pregnancy.

Lactation

Not recommended.

Side Effects

Flushing, fatigue, oedema, dizziness, headache, abdominal pain, nausea, palpitations, somnolence, Insomnia, headache, GI disturbances, myalgia, asthenia.