SPASMOMEN
OTILONIUM BROMIDE · by PHARMATEC
Composition
Tab 40 mg: Otilonium bromide 40 mg.
Indications & Dosage
GI spasm, premedication for GI procedure, GI disorders associated with anxiety and agitation: Adults: 1 tab 3 times daily. Children: Not recommended.
Contraindications
Myasthenia gravis, paralytic ileus, toxic mega colon, and prostatic enlargement pyloric stenosis, coma, stupor, hypersensitivity to the drug.
Precautions
Downs syndrome, elderly, gastro-esophageal reflux disease, diarrhoea, ulcerative colitis, autonomic neuropathy, acute myocardial infarction, hypertension, conditions characterized by tachycardia (including hyperthyroidism, cardiac insufficiency, cardiac surgery), pyrexia, and in individuals susceptible to angle-closure glaucoma.
Interactions
Amantadine, digoxin, phenothiazines atenolol, tricyclic antidepressants.
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated or not recommended.
Side Effects
Constipation, transient bradycardia (followed by tachycardia, palpitation and arrhythmias), reduced bronchial secretions, urinary urgency and retention, dilatation of the pupils with loss of accommodation, photo-phobia, dry mouth, flushing and dryness of the skin, confusion (particularly in the elderly), vomiting nausea, and giddiness. Rare: Angle-closure glaucoma may occur.