Composition
Tab 20 mg: Spironolactone 50 mg, furosemide 20 mg. Tab 40 mg: Spironolactone 50 mg, furosemide 40 mg.
Indications & Dosage
Refractory oedema, hypertension associated with secondary hyperaldosteronism: Adults: 1-4 tab daily. Children: Not recommended.
Contraindications
Severe or progressive renal failure, precomatose states associated with liver cirrhosis, hyperkalaemia, Addisons disease.
Precautions
Prostatic hypertrophy, impaired micturition, hepatic or renal impairment, diabetes, gout.
Interactions
K+ supplement, K-i4sparing diuretics, antihy-pertensives, ACE inhibitors, digitalis, lithium, aminoglycosides, cephalosporins, NSAIDs.
Pregnancy
Caution advised
Lactation
Not recommended.
Side Effects
GI upset, rash, gout, blood dyscrasias, gy-naecomastia.