Composition
Tab: Dienogest 2 mg
Indications & Dosage
Endometriosis: Females of childbearing age: 2 mg once daily, can be started on any day of cycle, dose to be taken without gap at the same time each day.
Contraindications
History or current cardiovascular disease, arterial disease and liver tumours. Diabetes with vascular involvement, sex hormone-dependent malignancies, undiagnosed vaginal bleeding, venous thromboembolism.
Precautions
Avoid in severe impairment, Diabetes; progestogens can decrease glucose tolerance, history of depression, history of ectopic pregnancy, history of gestational diabetes, patients at risk of osteoporosis, patients at risk of venous thromboembolism. Use non-hormonal contraceptives if required.
Interactions
Rifamycin, anticoagulants, antidepressants, antidiabetics, anti-epileptics, antifungals, antivirals, aprepitant, barbiturates, bosentan, cyclosporin, diuretics, dopaminer-gics, lipid-regulating drugs, muscle relaxants.
Side Effects
Alopecia, anxiety, asthenic conditions, breast abnormalities, depression, GI disorders, haemorrhage, headaches, hot flush, libido loss, mood altered, nausea, ovarian cyst, pain, skin reactions, sleep disorder, vomiting, vulvovaginal disorders, anaemia, dry eye, dyspnoea, hypotension, muscle spasms, oedema, palpitations, pelvic pain, tinnitus, glucose tolerance impaired., insulin resistance, menstrual cycle irregularities.